Persian-Angora Improvement (Suspect Feline Panleukopenia) After IgY and Curcuminoid Supplementation in Indopet_Id
DOI:
https://doi.org/10.33394/mvj.v5i1.15168Keywords:
panleukopenia, IgY, curcuminoid, immunobs, ampicillinAbstract
Panleukopenia merupakan penyakit yang disebabkan oleh parvovirus dan umumnya dikenal sebagai feline panleucopenia virus (FPV). Penyakit ini memiliki mortalitas dan morbilitas yang tinggi. Hewan yang belum divaksin menjadi salah satu faktor presdiposisi pada penyakit ini. Persentase mortalitas dapat mencapai 25-90%. Di sisi lain penggunaan antibodi pada kuning telur (IgY) terbukti dapat mencegah infeksi bakteri dan virus. Studi kasus ini bertujuan untuk mengetahui pengaruh pemberian IgY dan kurkumin pada kucing suspect FPV. Studi kasus ini menggunakan kucing berumur 9 bulan, ras campuran persia-angora berbulu putih. Pemeriksaan fisik menunjukkan rentang jantung normal, laju pernapasan normal, namun disertai suhu tubuh tinggi (40,10C). Berdasarkan anamnesis, kucing tersebut menderita anoreksia dan lesu selama hampir 6 hari diikuti diare selama satu hari. Ritme tidur tidak normal, ia tidur pada siang hari hingga pukul 14.00, berlanjut dari pukul 16.00 hingga keesokan harinya. Ia tidak divaksinasi dan tinggal di kandang ganda berisi 3 ekor kucing. Salah satu saudaranya mati karena panleukopenia setelah beberapa hari dirawat intensif di klinik hewan. Oleh karena itu, diagnosis dugaan panleukopenia diterapkan pada kucing tersebut. Kucing tersebut didiagnosis panleukopenia oleh dokter hewan. Terapi dan pengobatan yang disarankan oleh dokter hewan di Indopet_Id Petcare termasuk asupan makanan cair yang banyak disertai larutan gula, dosis ampisilin oral yang tepat (25 mg/kg) selama 5 hari dan satu bungkus Immunobs selama 7 hari. Kesimpulan yang didapatkan setelah pemberian terapi tersebut kondisi kucing semakin membaik, tanda-tanda dehidrasi berkurang, dan tidak ada tanda-tanda diare pada feses kucing.
References
Anggakusuma, C., C.C. Schang, L.M. Rachmawati, H. Frentzen, A. Pfaender, S. Brehrendt, P. Brown, R.J. Bankwitz, D. Steinmann, J. Ott, M. Meuleman, P. Rice, C.M. Ploss, A. Pietschmann, T. and E. Steinmann. (2012). Turmeric curcumin inhibit all entry of hepatitis C virus genotypes into liver cells. J. Gut, (63),1137-1149.
Basil, V. Peechakara B. V., H. Basit, M. Gupta. (2023). Ampicillin. StatPearls Publishing.
El-Kafrawy, S.A., A.T. Abbas, C. Oelkrug, M. Tahoon, S. Ezzat, A. Zumla, E.L. Azhar. (2023). IgY antibodies: The promising potential to overcome antibiotic resistance. Front Immunol, 20(14), 141065353.
Garigliany, M. Gilliaux, G. Jolly, S. Casanova, T. Bavrou, C. Commeren, K. Fett, T. Mauroy, A. Levy, E. Cassart, D. Peeters, D. Poncelet, L. And D. Desmecht. (2016). Feline Panleukopenia Virus (FPV) in cerebral neuron of young and adult cats. BMC Vet. Res, (12), 28.
Hamilton, A. E., and R. J. Gilbert. (2023). Curcumin Release from Biomaterials for Enhanced Tissue Regeneration Following Injury or Disease. Bioengineering, 10(2), 262.
Hartmann, K. (2017). Feline Panleukopenia Update on Prevention. The Thai Journal of Veterinary Medicine, 47, S101–S104.
Hovind, M. J., Berdal, J. E., Dalgard, O., & Lyngbakken, M. N. (2024). Impact of antibiotic therapy in patients with respiratory viral infections: a retrospective cohort study. Infectious Diseases, 56(12), 1031–1039. https://doi.org/10.1080/23744235.2024.2375592.
Millah, N. U., K. Agapietta, R. Laelatul, H. Novi, S. Kurniati, S. Bambang, W. Hastari, dan R. Warsito. (2014). The Effects of Turmeric Extract (Curcuma domestica Val) on Cigarette Smoke Cardiotoxicity in The Wistar Rats. Jurnal Sain Veteriner, (31)2, 2407-3733.
Mounce, B.C., T. Cesaro, L. Carrau, T. Vallet, and M. Vignuzzi. (2017). Curcumin inhibit Zika and Chikunguya virus infection by inhibit cellular binding. Antiviral Res, (142), 148-157.
Murphy, E.A, J.M. Davis, J.J. Clellan, B.T. Gordon, M.D. Carmichael. (2011). Curcumin effect on intestinal inflammation and tumorigenesis in the Apc min/plus mouse. J. Interferon Cytokine Res, (31), 219-226.
Rehme, Teresa, K. Hartmann, U. Truyen, Y. Zablotski and M. Bergmann. (2022). Feline Panleukopenia Outbreaks and Risk Factors in Cats in Animal Shelters. Viruses, 14(6), 1-14.
Truyen, L., D. Addie, S. Bellak, C. Boucraut, H. Egberink, T. Fyrmus, T. Gruffyd, K. Hartmann, M. J. Hosie, A. Lioret, H. Lutz, E. Marsilo, M.G. Pennisi, A.D. Radford, E. Thiry, and M.C. Horzinek. (2009). Feline panleukopenia: guidelines on prevention and management. J. Feline Med. Surg, (7), 538-546.
Urošević, M., L. Nikolić, I. Gajić, V. Nikolić, A. Dinić,* and V. Miljković. (2022). Curcumin: Biological Activities and Modern Pharmaceutical Forms. Antibiotics (Basel), 11(2), 135.
Xiaoyu, Li., L. Wang, Y. Zhen, S. Li, Y. Xu. (2015). Chicken egg yolk antibodies (IgY) as non-antibiotic production enhancers for use in swine production: a review. J. Animal Sci. and Biotech, 6(1), 40-50.
Zhao, H. M., R. Xu, X. Y. Huang, S. M. Cheng, M. F. Huang, H.Y Yue, X. Wang, Y. Zou, A. P Lu, and D.Y. Liu. (2016). Curcumin improves regulatory T-cells in gut-associated lymphoid tissue of colitis mice. World J. Gastroenterol, (22), 5374-538.
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